Study | n | Thyroxine dose/day | Cases of TSH suppression (%) | Definition of TSH suppression | |||||
---|---|---|---|---|---|---|---|---|---|
3 months | 6 months | 12 months | |||||||
London1 | 32 | 100 μg/m2 | 19 | 37 | 72 | < 6 mU/l | |||
SW England8 | 42 | Variable | 48 | 62 | 67 | < 10 mU/l | |||
Leicester | 25* | 37.5 μg | 52 | 80 | 88 | < 10 mU/l | |||
Norway5 | 42 | 50 μg | 86 | – | – | < 10 mU/l |
1-150 Four cases excluded: one because of definite non-compliance and three because of late treatment in mildly affected cases.