Conditions in which the lactate lowering effect of DCA has been demonstrated
| Condition | Animals | Humans |
|---|---|---|
| CLA | + | |
| Malaria | + | + |
| Diabetes mellitus | + | + |
| Hypoxia | + | + |
| Hypotension | + | + |
| Heart failure | + | + |
| Endotoxaemia | + | |
| Bacterial infection | + | |
| Cancer | + | |
| Liver failure | + | + |
| Renal failure | + | |
| Catecholamine excess | + | |
| Exercise | + | + |
From Stacpoole et al 6 15 and Krishnaet al. 16