Case details with results and side effects of period on cyclosporin
| Sex (age in years) | Duration of continuous prednisolone (years) | Other medication | Effect of cyclosporin | Side effects | |
|---|---|---|---|---|---|
| 1 | Girl (8) | 2 | Budesonide 1 mg/12 hours, terbutaline 5 mg when necessary | No benefit, abandoned after six months | Nil |
| 2 | Girl (15) | 0.8 | Fluticasone 1 mg/12 hours, terbutaline 5 mg when necessary, terbutaline subcutaneous infusion, salmeterol 100 μg/12 hours | Successful reduction in steroid dose, stopped due to side effect | Severe hirsutism |
| 3 | Girl (8) | 3 | Budesonide 1 mg/12 hours, salbutamol 5 mg when necessary, salmeterol 50 μg/ 12 hours, theophylline 200 mg at night | Initial successful reduction in prednisolone dose but relapsed within six months | Mild hirsutism |
| 4 | Boy (9) | 5 | Budesonide 1.5 mg/12 hours, terbutaline 1 mg when necessary, salmeterol 100 μg/12 hours | Weaned off prednisolone over 10 months, major improvement in height and weight centiles, back at school full time | 28% decline in glomerular filtration rate, no change in creatinine or blood pressure |
| 5 | Girl (10) | 5 | Budesonide 1.5 mg/12 hours, salbutamol 5 mg when necessary, salmeterol 100 μg/ 12 hours, theophylline 125 mg/12 hours | Weaned from prednisolone completely, major improvement in height/weight centiles | Transient lymphadenopathy, mild hirsutism |