Daily caffeine consumption in the first and third trimester and the associated risk of SIDS
| Caffeine consumption (mg/day) | No (%) SIDS infants | No (%) control infants | OR (95% CI) unadjusted† |
|---|---|---|---|
| First trimester | |||
| 0–99 | 108 (28.7) | 526 (33.3) | 1.00 |
| 100–199 | 67 (17.8) | 333 (21.1) | 0.95 (0.68 to 1.33) |
| 200–399 | 88 (23.3) | 434 (27.5) | 0.96 (0.71 to 1.31) |
| ⩾400 | 114 (30.2) | 288 (18.2) | 1.90 (1.41 to 2.57)*** |
| Third trimester | |||
| 0–99 | 109 (28.9) | 510 (32.3) | 1.00 |
| 100–199 | 68 (18.0) | 337 (21.3) | 0.93 (0.66 to 1.29) |
| 200–399 | 82 (21.8) | 456 (28.8) | 0.83 (0.61 to 1.14) |
| ⩾400 | 118 (31.3) | 278 (17.6) | 1.97 (1.46 to 2.66)*** |
1-151 Adjusted for infants’ age only.
Wald statistic p value:*** p<0.001