Table 3

Physiological measures in children with asthma (n = 15)  

BaselineFour weeksMedian changep value
FEV1 (% predicted)72.085.011NS
(60.5–81.5) (2)(73.5–93.3) (5)(−4.5–24.8)
FEF25–75 (% predicted)56.071.06.5NS
(45.0–67.5) (2)(56.5–77.8) (5)(−4.8–24.8)
PEFR (% predicted)81.387.88< 0.05
(62.3–95.8) (3)(70.5–101.9) (3–13)
PEFR variability (%)12.57.8−4.0< 0.05
(7.0 and 22.7) (4)(5.7–9.1) (5)(−11.1–1.2)
  • Results are expressed as median (interquartile range) (any missing values).

  • FEV1, forced expiratory volume in one minute; FEF25–75, forced expiratory flow from 25% to 75% of lung volume; PEFR, peak expiratory flow rate; PEFR variability, variations of PEFR between morning and evening.