M | Birth | Recurrent otitis media and lower respiratory tract infections | 1 Year 8 months | IgG3 deficiency | Wet lung syndrome at birth, minor stenosis of the trachea. Susceptibility to infections decreased |
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F | 9 Months | Purulent skin infections, recurrent otitis media, lower respiratory tract infections, failure to thrive | 12 Years | IgG3 deficiency, transient low IgG2 and high IgE | Severe atopic eczema and bronchial asthma. Susceptibility to infections decreased |
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M | 1 Month | Recurrent otitis media, maxillary sinusitis, and lower respiratory tract infections | 4 Years 1 month | IgG4 deficiency and transient low IgG2
| Susceptibility to infections decreased |
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F | 5 Months | Severe purulent tracheobronchitis with acute respiratory distress syndrome at age 5 months. Thereafter repeated lower respiratory tract infections | 5 Years 11 months | IgG4 deficiency | Subglottic stenosis caused by tracheobronchitis and prolonged intubation; operated on at 3 years. Susceptibility to infections decreased |
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M | 1 Year, 1 month | Severe S aureus lymphadenitis of the neck | 1 Year 2 months | IgG4 deficiency | After lymphadenitis no increased susceptibility to infections |
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F | 3 Months | Recurrent otitis media and lower respiratory tract infections | 3 Years 1 month | Transient low IgG2 | Gastro-oesophageal reflux and bronchial hyperreactivity. Susceptibility to infections decreased |
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M | 1 Year | Recurrent otitis media and maxillary sinusitis | 3 Years 6 months | Transient low IgG2 and IgG4
| Atopic eczema and bronchial asthma. Repeated maxillary sinusitis |