Table 2

Results of basal investigations in controls (n=133); results are median (10th–90th centile)

		Meal 1				Meal 2			Meal 3		Meal 4
		Before	After			Before	After		Before	After	Before	After
Group 1 (n=45)
Lactate (mmol/l)	1.18 (0.69–1.96)	1.50 (0.80–2.29)		1.16 (0.70–1.78)	1.40 (0.86–2.26)		1.19 (0.78–1.86)	1.55 (1.01–1.98)	1.16 (0.70–1.90)	1.52 (1.05–2.18)
Pyruvate (mmol/l)	0.09 (0.06–0.12)	0.13 (0.08–0.17)		0.10 (0.07–0.14)	0.12 (0.08–0.15)		0.11 (0.08–0.13)	0.12 (0.08–0.16)	0.10 (0.07–0.14)	0.12 (0.08–0.17)
L/P (mmol/mmol)	13.5 (8.7–20.7)	12.1 (8.7–18.5)		11.4 (7.9–19.6)	12.1 (9.4–17.4)		11.4 (8.5–17.5)	13.1 (9.7–16.5)	12.2 (8.9–18.7)	13.1 (9.2–17.5)
Group 2 (n=65)
Lactate (mmol/l)	0.80 (0.54–1.27)	1.29 (0.72–1.90)		0.80 (0.62–1.27)	1.18 (0.76–1.61)		0.84 (0.56–1.48)	1.09 (0.77–1.58)	0.80 (0.53–1.54)	1.24 (0.85–2.07)
Pyruvate (mmol/l)	0.08 (0.06–0.11)	0.12 (0.07–0.17)		0.09 (0.06–0.11)	0.10 (0.08–0.14)		0.09 (0.07–0.11)	0.10 (0.07–0.13)	0.09 (0.05–0.12)	0.11 (0.06–0.15)
L/P (mmol/mmol)	10.0 (7.0–16.3)	10.4 (7.6–14.2)		9.9 (7.2–14.3)	10.8 (7.5–15.5)		9.8 (6.6–14.4)	10.9 (7.6–15.8)	9.9 (6.8–15.0)	11.1 (8.3–15.3)
Group 3 (n=23)
Lactate (mmol/l)	0.71 (0.47–1.09)	1.26 (0.92–1.59)		0.97 (0.52–1.41)	1.13 (0.94–1.40)		0.80 (0.56–1.06)	1.09 (0.70–1.51)	0.75 (0.50–1.18)	1.10 (0.73–1.45)
Pyruvate (mmol/l)	0.08 (0.05–0.11)	0.12 (0.09–0.17)		0.09 (0.06–0.12)	0.10 (0.07–0.14)		0.09 (0.06–0.11)	0.10 (0.08–0.15)	0.08 (0.05–0.12)	0.11 (0.08–0.14)
L/P (mmol/mmol)	9.2 (6.4–14.5)	9.9 (7.0–12.4)		10.1 (6.2–15.8)	11.1 (8.0–14.8)		9.3 (6.5–14.5)	9.8 (7.4–13.8)	9.6 (5.5–12.4)	9.9 (7.3–12.3)
L/C(mmol/mmol)	Group 1: 0.09 (0.06–0.20); group 2: 0.06 (0.03–0.10); group 3: 0.04 (0.03–0.07).