Characteristics of patients in the two infusion groups before amphotericin B infusions
| Characteristic | Duration of infusion | ||
|---|---|---|---|
| One hour (group 1, n=12) | Four hours (group 2, n=12) | ||
| Males/females1-150 | 10/2 | 5/7 | |
| Age range (years) | 0.4-16.1 | 0.1-18.4 | |
| Mean (SD) age (years) | 5.7 (5.4) | 6.6 (6.5) | |
| No with neutropenia | 9 | 8 | |
| No with fever | 11 | 9 | |
| No with confirmed fungal infections | 2 | 4 | |
| Underlying diagnosis | |||
| Acute lymphocytic leukaemia | 2 | 4 | |
| Acute monocytic leukaemia | 3 | 4 | |
| Non-Hodgkin’s lymphoma | 0 | 1 | |
| Rhabdomyosarcoma | 1 | 0 | |
| Neuroblastoma | 1 | 0 | |
| Wilms’ tumour | 0 | 1 | |
| Severe combined immunodeficiency | 0 | 1 | |
| Immunodeficiency | 1 | 0 | |
| Bone marrow transplant | 1 | 0 | |
| Aplastic anaemia | 1 | 0 | |
| Short gut syndrome | 0 | 1 | |
| Chronic candidal mastoiditis | 1 | 0 | |
| Histiocytosis X | 1 | 0 | |
↵1-150 p Value = 0.04.