Table 3

Results of kwashiorkor cases: milk v maize diet

OutcomesMilk diet (n=55)Maize diet (n=45)p Value
Clinical
 Mortality (%)2 (3.6)10 (22.2)0.01
 Clinical sepsis (%)17 (30.9)27 (60.0)0.01
 Diarrhoea during initial week (%)35 (63.6)14 (31.1)0.002
 % Days with diarrhoea in hospital34.8 (29.8 to 39.8)24.3 (17.8 to 30.8)0.01
 Weight gain:
  Mean No of days5.3 (3.9 to 6.7)2.7 (1.7 to 3.7)0.01
  In g/kg/day3-150 4.4 (3.4 to 5.5)2.9 (2.1 to 3.7)0.03
 Days in hospital15.5 (13.9 to 17.1)15.8 (13.9 to 17.7)0.81
 Oedema resolved (days)9.3 (7.7 to 10.9)8.8 (6.6 to 11.0)0.71
Permeability
 Mean urine output (ml/kg/hour testing)3-150 1.29 (1.13 to 1.45)1.21 (1.05 to 1.37)0.51
 Mean % lactulose recovery3-150 0.145 (0.12 to 0.17)0.192 (0.16 to 0.23)0.03
 Mean % rhamnose recovery3-150 1.08 (0.90 to 1.29)0.99 (0.83 to 1.19)0.51
 Differences in L-R permeability3-150 3-151
  Improved ratio (%)44 (57.9)25 (41.7)0.09
 Worsened ratio (%)19 (25.0)28 (46.7)0.01
 Mean differences in L-R ratio6.4 (1.7 to 11.1)−6.8 (−16.8 to 5.0)0.001
  • 3-150 Geometric mean (95% confidence interval), L-R ratios × 100.

  • 3-151 Differences between weekly tests 1-2 and 1-3.