Patients with undetectable metabolites: doctor’s assessment of possible reasons for non-compliance
| Patient No | Age (years) | Likely non-compliant? | Possible reason for non-compliance |
|---|---|---|---|
| 1 | 12 | Yes | Tablets made her feel ill and were a daily reminder that she had cancer |
| 2 | 5 | Yes | Parents had idiosyncratic views about treatment |
| 3 | 15 | Yes | Lack of motivation/supervision |
| 4 | 7 | Possible | Lack of supervision/chaotic family |
| 5 | 5 | Yes | Difficult family circumstances with frequent social work input |
| 6 | 11 | No | No obvious problem |
| 7 | 14 | Yes | School and behavioural problems. Admitted to not taking tablets |
| 8 | 18 | Yes | Fed up with treatment, wanted to be ‘normal’. Refused bone marrow transplantation. Was on prolonged maintenance treatment |
| 9 | 6 | Yes | Complex social situation. Family accepted that treatment not given. Maternal grandmother blamed |