Clinical features of 42 infants at presentation with colitis
| Male:female: | 26:16 | 1.6:1 | Total | Percentage | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| AC | NSC | SC | IBD | AIE | |||||||
| No of cases | 26 | 4 | 3 | 5 | 4 | 42 | 100.0 | ||||
| Age of onset < 6/12 | 18 | 3 | 1 | 3 | 3 | 28 | 66.7 | ||||
| Signs and symptoms | |||||||||||
| Diarrhoea | 24 | 3 | 3 | 5 | 4 | 39 | 92.8 | ||||
| Rectal bleeding | 20 | 4 | 1 | 5 | 1 | 31 | 73.8 | ||||
| Weight loss | 18 | 2 | 3 | 4 | 3 | 30 | 71.4 | ||||
| Abdominal pain | 13 | 2 | 0 | 2 | 0 | 17 | 40.5 | ||||
| Anorexia | 9 | 2 | 2 | 1 | 2 | 16 | 38.1 | ||||
| Recurrent infections | 6 | 1 | 3 | 3 | 1 | 14 | 33.3 | ||||
| Abdominal distention | 8 | 0 | 1 | 0 | 1 | 10 | 23.8 | ||||
| Constipation | 2 | 1 | 0 | 0 | 0 | 3 | 7.1 | ||||
| Vomiting | 10 | 1 | 1 | 1 | 1 | 14 | 33.3 | ||||
| Fever | 2 | 0 | 3 | 1 | 1 | 7 | 16.7 | ||||
| Consanguinity | 0 | 1 | 0 | 1 | 2 | 4 | 9.5 | ||||
| Family history | |||||||||||
| Atopy/asthma | 15 | 1 | 0 | 3 | 1 | 20 | 47.6 | ||||
| IBD | 3 | 0 | 0 | 1 | 0 | 4 | 9.5 | ||||
| Atopy in patient | 9 | 0 | 1 | 1 | 1 | 12 | 28.6 | ||||
| Feeding | |||||||||||
| Breast milk only | 8 | 2 | 1 | 1 | 2 | 14 | 33.3 | ||||
| Cows’ milk formula | 8 | 1 | 1 | 1 | 0 | 11 | 28.6 | ||||
| Soya formula | 3 | 0 | 0 | 0 | 0 | 3 | 7.1 | ||||
| Mixed | 7 | 1 | 1 | 3 | 1 | 13 | 30.9 | ||||
| Weight | |||||||||||
| < 3rd centile | 15 | 2 | 3 | 3 | 3 | 26 | 61.9 | ||||
| Height | |||||||||||
| < 3rd centile | 8 | 1 | 3 | 2 | 1 | 15 | 35.7 | ||||
AC = allergic colitis; NSC = non-specific colitis; SC = severe combined immunodeficiency; IBD = inflammatory bowel disease (ulcerative colitis and Crohn’s disease); AIE = autoimmune enterocolitis.