No | Age | Sex | Diagnosis | Previous antiepileptic drugs | Status | Midazolam | Outcome | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type | Duration (minutes) | Antiepileptic drugs received to control | Rate (μg/kg/min) | Cessation of seizures (minutes) | Side effects | ||||||||||||
1 | 2 months | M | Acute purulent meningitis | Nil | GTC | 40 | DZP PR, IV, PHT IV | 1 | 15 | Nil | No recurrence | ||||||
2 | 10 years | M | Idiopathic epilepsy | SVA, VGB, LTG, PHT, ETH | GTC | 45 | DZP PR, IV | 1 | 30 | Nil | No recurrence | ||||||
3 | 10 years | F | Idiopathic epilepsy | — | GTC | 30 | PHT IV | 1 | 15 | Nil | No recurrence | ||||||
4 | 4 years | F | Neurological degeneration | SVA | Partial motor/MYO | 300 | DZP PR | 2.5 | 50 | Nil | Several | ||||||
5 | 1 year | M | Postencephalitic sequalae | PHT, PHB | GTC | 180 | DZP IV (3) | 2.5 | 60 | Nil | No recurrence | ||||||
6 | 2 months | M | Cerebrovascular accident | SVA, PHT | GTC | 120 | DZP IV | 1.5 | 25 | Nil | No recurrence | ||||||
7 | 6 months | M | Acute purulent meningitis | — | GTC | 45 | DZP IV, PHT IV | 1.5 | 25 | Nil | No recurrence | ||||||
8 | 8 months | M | Acute purulent meningitis | — | Partial motor | 60 | DZP IV, PHB IV | 1 | 25 | Nil | No recurrence | ||||||
9 | 5 years | M | Chronic encephalitis | SVA, CLZ | GTC, MYO | 1440 | DZP PR, IV, PHT IV | 5 | 220 | Nil | Lost to follow up | ||||||
10* | 3 years | M | Idiopathic epilepsy | CBZ | MYO, T | 90 | DZP IV | 2 | 40 | Nil | No recurrence | ||||||
11 | 3 years | M | Idiopathic epilepsy | — | MYO, astatic | 30 | DZP PR | 1 | 10 | Nil | Recurred twice | ||||||
12 | 13 years | M | Cerebrovascular accident | — | GTC | 40 | DZP IV | 2 | 60 | Nil | No recurrence | ||||||
13* | 4 years | M | Idiopathic epilepsy | CBZ, SVA, CLZ | MYO, T | 120 | DZP PR (2) | 2 | 25 | Nil | No recurrence | ||||||
14 | 9 years | F | Idiopathic epilepsy | SVA, CBZ | Complex partial | 65 | PHT IV | 2 | 30 | Nil | No recurrence | ||||||
15 | 3 years | F | Acute meningoencephalitis | — | Complex partial | 60 | PHT IV | 2.5 | 50 | Nil | No recurrence | ||||||
16 | 6 months | M | Cerebral dysgenesis | PHB, PHT, SVA | GTC | 720 | DZP PR, PHT IV | 5 | 240 | Nil | Recurred twice | ||||||
17 | 3 years | M | Idiopathic epilepsy | SVA, PHT | GTC, MYO | 120 | PHT IV | 2 | 60 | Nil | No recurrence | ||||||
18 | 7 years | M | Idiopathic epilepsy | SVA, PHT | GTC | 45 | PHT IV | 2 | 60 | Nil | No recurrence | ||||||
19 | 2 years | F | Acute meningoencephalitis | — | GTC | 30 | PHT IV, PHB IV | 1 | 15 | Spo 2 90% | No recurrence | ||||||
20 | 2.5 years | M | Acute meningoencephalitis | — | GTC, dystonic | 60 | PHT IV, PHB IV | 1.5 | 25 | Spo 2 90% | No recurrence |
GTC = generalised tonic-clonic; T = tonic; MYO = myoclonic; IV = intravenous; PR = per rectum; DZP = diazepam; PHT = phenytoin sodium; PHB = phenobarbitone; SVA = sodium valproate; CBZ = carbamazepine; VGB = vigabatrin; LTG = lamotrigine; ETH = ethosuximide; Spo2 = oxygen saturation; * Lennox-Gastaut syndrome status.