Clinical and molecular findings in our series of patients with CTHDs
| Cardiac defect | Total No of patients | Syndromic patients | Isolated patients | ||||||
|---|---|---|---|---|---|---|---|---|---|
| DG/VCF | Other | ||||||||
| With del22 | Without del22 | With del22 | Without del22 | With del22 | Without del22 | ||||
| TF | 161 | 16 | 7 | 0 | 33 | 0 | 105 | ||
| TGA | 45 | 2 | 1 | 0 | 0 | 1 | 41 | ||
| Corrected TGA | 30 | 0 | 0 | 0 | 0 | 0 | 30 | ||
| TF with PA | 29 | 13 | 3 | 0 | 3 | 0 | 10 | ||
| Heterotaxia | 20 | 0 | 0 | 0 | 20 | 0 | 0 | ||
| DORV | 14 | 1 | 1 | 0 | 2 | 0 | 10 | ||
| TA | 12 | 2 | 1 | 0 | 2 | 0 | 7 | ||
| IAA | 4 | 3 | 0 | 0 | 1 | 0 | 0 | ||
Abbreviations: del22, microdeletion 22 q11; DG, DiGeorge syndrome; DORV, double outlet right ventricle; IAA, interrupted aortic arch; PA, pulmonary atresia; TA, truncus arteriosus; TF, tetralogy of Fallot; TGA, transposition of the great arteries; VCF, velocardiofacial syndrome.