Indications | (i) Raised ICP | (i) Allergic reactions |
(ii) Preparation for neurosurgery | Prevention | |
(iii) Antiemetic | Treatment | |
(ii) Anaphylaxis | ||
Drug | Dexamethasone | Hydrocortisone |
Route | Oral, intravenous | Intravenous |
Starting dose | 5-10 mg/m2/day in divided dosesOR | 4 mg/kg bolus |
0.5 mg/kg/day in divided doses | ||
Maximum | 16 mg/day | 200 mg bolus |
Notes | Smaller doses if possible | 2 mg/kg 6 hourly if needed |
Trial of 3-5 day courses for raised ICP | Only use if chlorpheniramine inadequate, or anaphylaxis | |
Only use as antiemetic if other drugs not effective |
All patients prescribed steroids receive concurrent oral nystatin and an antacid (magnesium trisilicate preparation).