RT Journal Article SR Electronic T1 Can urgency classification of the Manchester triage system predict serious bacterial infections in febrile children? JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 715 OP 722 DO 10.1136/adc.2010.207845 VO 96 IS 8 A1 Ruud G Nijman A1 Rob LJ Zwinkels A1 Mirjam van Veen A1 Ewout W Steyerberg A1 Johan van der Lei A1 Henriëtte A Moll A1 Rianne Oostenbrink YR 2011 UL http://adc.bmj.com/content/96/8/715.abstract AB Objective To evaluate the discriminative ability of the Manchester triage system (MTS) to identify serious bacterial infections (SBIs) in children with fever in the emergency department (ED) and to study the association between predictors of SBI and discriminators of MTS urgency of care. Methods This prospective observational study included 1255 children with fever (1 month–16 years) attending the ED of the Erasmus MC – Sophia Children's Hospital, Rotterdam, The Netherlands in 2008–9. Triage urgency was determined with the MTS (urgency (U) level 1–5). The relationship between triage urgency and SBI was assessed with multivariable logistic regression, including effects of age, sex and temperature. Discriminative ability was assessed by receiver operating characteristic curve analysis. Results SBI prevalence was 11% (n=131, 95% CI 9% to 12%). The discriminative value of the MTS for predicting SBI was 0.57 (95% CI 0.52 to 0.62), and the MTS did not contribute to a model including age, sex and temperature. The sensitivity of the MTS (U1–2 vs U3–5) to detect SBI was 0.42 (95% CI 0.33 to 0.51) and specificity was 0.69 (95% CI 0.66 to 0.72). MTS high urgency discriminators include several known predictors of SBI, such as fever, work of breathing, meningism and oxygen saturation, but apply to non-SBI children as well. Conclusion The MTS has poor discriminative ability to predict the presence of SBIs in children presenting with fever to the paediatric ED. Important predictors of SBI are represented within the MTS, but are used in a different way to classify urgency.