TY - JOUR T1 - Lethal cardiomyopathy in epidermolysis bullosa associated with amitriptyline JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 871 LP - 872 DO - 10.1136/adc.2004.068775 VL - 90 IS - 8 AU - S M Taibjee AU - P Ramani AU - R Brown AU - C Moss Y1 - 2005/08/01 UR - http://adc.bmj.com/content/90/8/871.abstract N2 - There are previous reports of dilated cardiomyopathy (DCM) in recessive dystrophic epidermolysis bullosa (RDEB), a debilitating blistering skin disorder. The pathogenesis of DCM in RDEB remains uncertain, although dietary deficiency of selenium and carnitine have been implicated. A 6 year old girl with RDEB who died of DCM is reported; attention is drawn to the possible role of two potentially cardiotoxic drugs, amitriptyline and cisapride. ER -