TY - JOUR T1 - Treatment of infantile spasms JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 817 LP - 817 VL - 90 IS - 8 A2 - , Y1 - 2005/08/01 UR - http://adc.bmj.com/content/90/8/817.abstract N2 - Infantile spasms are usually treated with either steroid (oral corticosteroid or intramuscular adrenocorticotropic hormone) or vigabatrin. These treatments have been compared in a UK multicentre trial (Andrew L Lux and colleagues. Lancet2004;364:1773–8OpenUrlCrossRefPubMedWeb of Science) A total of 107 infants aged 2–12 months with infantile spasms (not due to tuberous sclerosis) were randomised (2:1:1) at 150 centres to vigabatrin, prednisolone, or tetracosactide. Vigabatrin dosage was 25 mg/kg twice on day 1 and 50 mg/kg twice daily from day 2, … ER -