PT - JOURNAL ARTICLE AU - L Spitz AU - K Roth AU - E M Kiely AU - R J Brereton AU - D P Drake AU - P J Milla TI - Operation for gastro-oesophageal reflux associated with severe mental retardation. AID - 10.1136/adc.68.3.347 DP - 1993 Mar 01 TA - Archives of Disease in Childhood PG - 347--351 VI - 68 IP - 3 4099 - http://adc.bmj.com/content/68/3/347.short 4100 - http://adc.bmj.com/content/68/3/347.full SO - Arch Dis Child1993 Mar 01; 68 AB - One hundred and seventy six children with severe mental retardation underwent a fundoplication for considerable gastro-oesophageal reflux. There were six 'early' (3%) deaths and five 'late' deaths. Major complications developed in 17 (10%) children whereas 86 (49%) had 'minor' complications. A revision operation was required in 27 patients. Overall 142 (81%) children achieved a good result. In spite of the high complication rate and the need for a secondary operation in 15% of the patients, the quality of life for these children and their parents and carers is greatly improved by antireflux surgery.