RT Journal Article
SR Electronic
T1 Cardiac rhabdomyomata in tuberous sclerosis: their course and diagnostic value.
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 196
OP 200
DO 10.1136/adc.64.2.196
VO 64
IS 2
A1 H C Smith
A1 G H Watson
A1 R G Patel
A1 M Super
YR 1989
UL http://adc.bmj.com/content/64/2/196.abstract
AB Echocardiography was performed in 60 people with tuberous sclerosis to ascertain the prevalence and course of cardiac rhabdomyomata at different ages. Twenty five (58%) of 43 children had tumours, but only three (18%) of 17 adults. The tumours tended to remain the same size through childhood. Only three infants were included but evidence from this and some published case reports suggest that the tumours tend to regress in early infancy and again in adolescence. The prevalence of tumours in young infants with tuberous sclerosis is likely to be considerably above 50%. As other signs of tuberous sclerosis are usually absent at this age echocardiography may afford the most useful diagnostic test in early infancy.