RT Journal Article
SR Electronic
T1 Reye's syndrome; diagnosis by muscle biopsy?
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 287
OP 291
DO 10.1136/adc.56.4.287
VO 56
IS 4
A1 Y Shapira
A1 R Deckelbaum
A1 M Statter
A1 A Tennenbaum
A1 M Aker
A1 R Yarom
YR 1981
UL http://adc.bmj.com/content/56/4/287.abstract
AB Three children with Reye's syndrome are described. One child died, the second had mild and transient illness, and the third had recurrent episodes. In all 3 children a muscle biopsy showed pronounced infiltration of the myofibres with fat microdroplets as shown by the oil red O stain and by electron microscopical examination. We suggest that needle biopsy of muscle may be a quick and safe aid to the diagnosis of Reye's syndrome, and may be preferable to liver biopsy in view of the pronounced tendency to bleed in Reye's syndrome.