RT Journal Article
SR Electronic
T1 Excretion of polyamines by children with Beckwith's syndrome.
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 40
OP 42
DO 10.1136/adc.55.1.40
VO 55
IS 1
A1 G B Barlow
YR 1980
UL http://adc.bmj.com/content/55/1/40.abstract
AB The urinary excretion of the polyamines--putrescine, spermidine, and spermine--was measured in 7 children with Beckwith's syndrome. Putrescine excretion was raised and spermidine excretion reduced. The raised putrescine and the low spermidine ratios were highly significant. These results are consistent with a disturbance in a metabolic pathway under growth hormone-like regulation.