PT - JOURNAL ARTICLE AU - G B Barlow TI - Excretion of polyamines by children with Beckwith's syndrome. AID - 10.1136/adc.55.1.40 DP - 1980 Jan 01 TA - Archives of Disease in Childhood PG - 40--42 VI - 55 IP - 1 4099 - http://adc.bmj.com/content/55/1/40.short 4100 - http://adc.bmj.com/content/55/1/40.full SO - Arch Dis Child1980 Jan 01; 55 AB - The urinary excretion of the polyamines--putrescine, spermidine, and spermine--was measured in 7 children with Beckwith's syndrome. Putrescine excretion was raised and spermidine excretion reduced. The raised putrescine and the low spermidine ratios were highly significant. These results are consistent with a disturbance in a metabolic pathway under growth hormone-like regulation.