RT Journal Article SR Electronic T1 Neurological complications of beta-thalassaemia major. JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 977 OP 979 DO 10.1136/adc.52.12.977 VO 52 IS 12 A1 D Sinniah A1 V Vignaendra A1 K Ahmad YR 1977 UL http://adc.bmj.com/content/52/12/977.abstract AB Neurological complications in beta-thalassaemia major are uncommon, with cerebral ischaemic episodes related to severe anaemia or convulsions as the most usual manifestations. Two such cases of children of 6 and 8 years are reported. Cerebral venous infarction is advanced as the probable cause of the symptoms. Caution should be exercised in giving rapid, large blood transfusions to thalassaemic patients adapted to long-standing severe anaemia.