Estimation of glomerular filtration rate from plasma creatinine concentration in children

Arch Dis Child. 1976 Nov;51(11):875-8. doi: 10.1136/adc.51.11.875.

Abstract

The relation between the true plasma creatinine concentration (Pc) and the glomerular filtration rate corrected for body surface area (GFR/SA) was investigated in 108 individuals, and the following formula was derived: GFR/SA (ml/min per 1-73m2SA) = 0-43 Ht (cm)/Pc (mg/100 ml). This formula was tested in a second group of 83 children, and its accuracy and precision was compared to the 24-hour creatinine clearance. It was found to be superior to the creatinine clearance overall, and was as good, even if all results involving suspect 24-hour-urine collections were eliminated from analysis. The formula in SI usage is: GFR/SA (ml/min per 1-73 m2SA) = 38 Ht (cm)1Pc (mumol/l).

MeSH terms

  • Adolescent
  • Adult
  • Body Surface Area
  • Child
  • Child, Preschool
  • Creatinine / blood*
  • Creatinine / urine
  • Glomerular Filtration Rate*
  • Humans
  • Infant
  • Kidney Diseases / blood
  • Kidney Diseases / physiopathology

Substances

  • Creatinine