Elsevier

Brain and Development

Volume 16, Issue 2, March–April 1994, Pages 165-167
Brain and Development

Enteral formula feeds interfere with phenytoin absorption

https://doi.org/10.1016/0387-7604(94)90058-2Get rights and content

Abstract

Two children treated for status epilepticus had low plasma phenytoin levels during enteral feeding, despite adequate oral dosage. The target range (10–20 mg/l) was achieved when feeds were stopped, or when intravenous phenytoin was used. Enteral feeding may interfere with the absorption of oral phenytoin thereby compromising seizure control.

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