Elsevier

The Lancet

Volume 335, Issue 8693, 7 April 1990, Pages 862-863
The Lancet

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Fatal fulminant hepatitis in an infant with human herpesvirus-6 infection

https://doi.org/10.1016/0140-6736(90)90983-CGet rights and content

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    Her hepatitis symptoms improved, but those of colitis did not, following intravenous ganciclovir and oral valganciclovir treatments [169]. However, some cases of encephalitis associated with HHV6 or HHV7 [170–174], and fulminant hepatitis due to HHV6 [175–178] have been reported in otherwise healthy individuals based on serology tests and/or the detection of viral DNA in CSF and/or whole blood. Patients who developed meningoencephalitis following HHV6 infection may also have ES manifestations [179,180].

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  • Fulminant hepatic failure attributed to infection with human herpesvirus 6 (HHV-6) in an immunocompetent woman: A case report and review of the literature

    2016, Journal of Clinical Virology
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    In both children and adults, upper respiratory tract symptoms and a rash may precede organ failure by days to weeks [7–9,13,14,33,36,43]. After a fatal FH case ascribed to primary HHV-6 infection was reported in an infant [8], several cases have been reported, primarily in very young children [26–28,35]. HHV-6 has rarely been implicated as a cause of non-A, non-B, non-C (NABC) hepatitis in immunocompetent adults [13,19,24].

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