Skip to main content
Log in

Prenatal detection of internal urinary system's anomalies

A registry-based study

  • Published:
European Journal of Epidemiology Aims and scope Submit manuscript

Abstract

Prenatal diagnosis performed by ultrasound scan is now a routine part of antenatal care in our region. How many fetal anomalies are actually detected by this procedure? We have used our registry of congenital malformations to answer this question regarding to Internal Urinary System (IUS) anomalies. The mean time of detection of IUS anomalies was 29 weeks of pregnancy (12–39). The sensitivity of prenatal diagnosis of IUS anomalies by ultrasonographic examination was 59.3% for isolated malformations (fetuses with only one anomaly) and 46.0% for multiple malformed children with IUS anomalies. For all cases of IUS anomalies the percentage of prenatal detection was 56.0. Termination of pregnancy was performed in 9.4% of the cases.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Sollie EJ, Van Geijn HP, Arts NFT. Validity of a selective policy for ultrasound examination of fetal congenital anomalies. Eur J Obstet, Gynecol Reprod Biol 1988; 27: 125–132.

    Google Scholar 

  2. Constantine G McCormack J. Comparative audit of booking and mid-trimester ultrasound scans in the prenatal diagnosis of congenital anomalies. Prenat Diagn 1991; 11: 905–914.

    Google Scholar 

  3. Greig JD Raine PAM, Young DG, Azmy AF, Ruth Mac Kenzie J, Danskin F, Whittle MJ, Mac Nay NG. Value of antenatal diagnosis of abnormalities of the urinary tract. Br Med J 1989; 289: 1417–1419.

    Google Scholar 

  4. Stoll C, Roth MP. The Northeastern France birth defects monitoring system. In: Marois M (ed), Prevention of physical and mental congenital defects, Part B. New York: Alan R. Liss, 1985: 157–162.

    Google Scholar 

  5. SAS/STAT TM Guide for Personal computers, 8th ed. Cary, NC: SAS Institute. Sharland G, Allan LD: Screening for congenital heart disease prenatally. Results of a 2 1/2 year study in the South East Thames region, Br J Obstet Gynecol 1992; 99: 220–225.

    Google Scholar 

  6. Campbell S, Pearce JM. The prenatal diagnosis of fetal structural anomalies by ultrasound. Clin Obstet Gynecol 1983; 10: 475–506.

    Google Scholar 

  7. Copel JA, Pilu G, Green J, Hobbins JC, Kleinman CS. Fetal echocardiographic screening for congenital heart disease: The importance of the four-chamber view. Am J Obstet Gynecol 1987; 157: 648–655.

    Google Scholar 

  8. Hobbins JC, Grannum PAT, Berkowitz RL, Silverman R, Mahoney MJ. Ultrasound in the diagnosis of congenital anomalies. Am J Obstet Gynecol 1979; 134: 331–345.

    Google Scholar 

  9. Vintzileos AM, Campbell WA, Nochimson DJ, Weinbaum PJ. Antenatal evaluation and management of ultrasonically detected fetal anomalies. Obstet Gynecol 1987; 69: 640–660.

    Google Scholar 

  10. Brons JTJ, Van Der Harten HJ, Van Geijn HP, Wladimiroff JW, Niermeijer MF, Lindhout D, Stuart PA, Meijer CJLM, Artz NFT. Prenatal ultrasono-graphic diagnosis of radial-ray reduction malformations. Prenat Diagn 1990; 10: 279–288.

    Google Scholar 

  11. Sabbagha RE, Sheikh S, Tamua RK, Dal Compo S, Simpson JL, Depp R, Gerbie AB. Predictive value, sensitivity and specificity of ultrasonic targeted imaging for fetal anomalies in gravid women at high risk for birth defects. Am J Obstet Gynecol 1985; 152: 822–827.

    Google Scholar 

  12. Persson PH, Kullander S. Long-term experience of general ultrasound screening in pregnancy. Am J Obstet Gynecol 1983; 146: 942.

    Google Scholar 

  13. Horger EO, Shashidhar PG. Ultrasound in the diagnosis of fetal malformations. Am J Obstet Gynecol 1983; 147: 163.

    Google Scholar 

  14. Sarda P, Bard H, Teasdale F, Grignon A. The importance of an antenatal ultrasonographic diagnosis of correctable fetal malformation. Am J Obstet Gynecol 1983; 147: 443–445.

    Google Scholar 

  15. Quinlam RW, Cruz AC, Huddleston JF. Sonographic detection of fetal urinary-tract anomalies. Obstet Gynecol 1986; 67: 558–565.

    Google Scholar 

  16. Lys F, De Walls P, Borlee-Grimee I, Billiet A, Vincottemols M, Levi S. Evaluation of routine ultrasound examination for the prenatal diagnosis of malformations. Eur J Obstet Gynecol Reprod Biol 1989; 30: 101–109.

    Google Scholar 

  17. Palcoux JB, Lemery D, Vanlieferinghen P, Desvignes V, Francannet P, Dechelotte P. Bilan du dépistage antenatal des uropathies malformatives sur 3 ans (1988–1990) dans le département du Puy-de-Dôme. P édiatrie 1992; 47: 699–703.

    Google Scholar 

  18. Livera LN, Brookfield DSK, Egginton JA, Hawnaur JM. Antenatal ultrasonography to detect fetal renal abnormalities: A prospective screening programme. Br MedJ 1989; 298: 1421–1423.

    Google Scholar 

  19. Barakat AJ, Butler MG, Cobb CG, Coursey JW, Shah D. Reliability of ultrasound in the prenatal diagnosis of urinary tract abnormalities. Pediatr Nephrol 1991; 5: 12–14.

    Google Scholar 

  20. Clarke NW, Gough DSC, Cohen SJ. Neonatal urological ultrasound: Diagnostic inaccuracies and pitfalls. Arch Dis Child 1989; 64: 578–580.

    Google Scholar 

  21. Madarikan BA, Hayward C, Roberts GM, Lari J. Clinical outcome of fetal uropathy. Arch Dis Child 1988; 63: 961–963.

    Google Scholar 

  22. Johnson CE, Elder JS, Judge NE, Adeeb FN, Grisoni ER, Fattlar DC. The accuracy of antenatal ultrasonography in identifying renal abnormalities. AJDC 1992; 146: 1181–1184.

    Google Scholar 

  23. Helin I, Persson PH. Prenatal diagnosis of urinary tract abnormalities by ultrasound. Pediatrics 1986; 78: 879–883.

    Google Scholar 

  24. Gunn TR, Mora JD, Pase P. Outcome after antenatal diagnosis of upper urinary tract dilatation by ultrsound. Arch Dis Child 1988; 63: 1240–1243.

    Google Scholar 

  25. Hobbins JC, Romero R, Grannum P, Berkowitz RL, Cullen M, Mahoney M. Antenatal diagnosis of renal anomalies with ultrasound. Obstructive uropathy. Am J Obstet Gynecol 1984; 148: 868–877.

    Google Scholar 

  26. Avni EF, Rodesch F, Schulman CC. Fetal uropathies: Diagnostic pitfalls and management. J Urol 1985; 134: 921–925.

    Google Scholar 

  27. Grignon A, Filion R, Filitrault D. et al. Urinary tract dilatation in utero: Classification and clinical applications. Radiology 1986; 160: 645–647.

    Google Scholar 

  28. Turnock RR, Shawis R. Management of fetal urinary tract abnormalities detected by ultrasonography. Arch Dischild 1984; 59: 962–965.

    Google Scholar 

  29. Hutson JM, McNay MB, McKenzie JR, Whittle MJ, Young DG, Raine PAM. Antenatal diagnosis of surgical disorders by ultrasonography. Lancet 1985 (i): 621–623.

  30. Pocock RD, Witcombe JB, Andrews HS, Berry PJ, Frank JD. The outcome of antenatally diagnosed urological abnormalities. Br J Urol 1985; 57: 788–792.

    Google Scholar 

  31. De Luca FG. The status of prenatal diagnosis and fetal surgery. Pediatr Surg Int 1987; 2: 259–266.

    Google Scholar 

  32. Elder JS, Duckett JW, Snyder HW. Intervention for fetal obstructive uropathy: Has it been effective? Lancet 1987 (i): 1007–1010.

  33. Luck CA. Value of routine ultrasound scanning at 19 weeks: A four year study of 8849 deliveries. Br Med J 1992; 304: 1474–1478.

    Google Scholar 

  34. Chitty LS, Hung GH, Moore J, Lobb MO. Effectiveness of routine ultrasonography in detecting fetal structural abnormalities in a low risk population. Br Med J 1991; 303: 1165–1169.

    Google Scholar 

  35. Brocks V, Vang J. Routine examination by ultrasound for the detection of fetal malformations in a low risk population. Fetal Diagn Ther 1991; 6: 37–45.

    Google Scholar 

  36. Stoll C, Alembik Y, Dott B, Roth MP, Sauvage P. Risk factors in internal urinary system malformations: Pediatr Nephrol 1992; 4: 319–323.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stoll, C., Alembik, Y., Dott, B. et al. Prenatal detection of internal urinary system's anomalies. Eur J Epidemiol 11, 283–290 (1995). https://doi.org/10.1007/BF01719432

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01719432

Key words

Navigation