eLetters

1151 e-Letters

published between 2014 and 2017

  • "Human factors matter" - Statistical analysis of performance of trigger systems misses the point

    Chapman et al (1) present a valuable evaluation of the performance characteristics of 18 commonly used paediatric early warning systems. They observed that the performance of the 12 “scoring” systems (where cumulative component values for vital signs are used to identify thresholds for escalation of care) was superior to 6 “trigger” systems (where breaching set thresholds for one or more vital signs lead to escalation without the need for adding numerical scores), based on sensitivity, specificity and area under the operating curve (AUROC). Although they do not specifically claim that this finding should be extrapolated to suggest that all scoring systems outperform trigger systems, this is the implication both in the results and discussion section. Indeed, the associated editorial by Lillitos & Maconochie confirms this implied conclusion, when they state that “In conclusion…overall, PEWS perform better than Trigger systems.” (2)

    We contend that this is an erroneous and misleading conclusion and far outstrips the scope and methodology of the study. Firstly, the findings are related to the performance of 16 specific tools and no comment can be made about whether it is the Trigger or the Score aspects which are responsible for this difference. Using the analogy of a therapeutic trial, there can be no basis to conclude that this is a “class effect” rather than specific to each tool. Secondly, the authors themselves recognise that it is the thresholds for escalation...

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  • Acute, unplanned paediatric admissions and earlier consultant review
    Julian M Sandell

    The team from Evelina are to be commended for questioning the current direction of travel of acute hospital practice, seeking to find "policy- based evidence" supporting the drive for increasingly consultant-delivered healthcare and their detailed report should help inform wider discussions, not just in paediatrics but across the entire spectrum of acute hospital medicine.

    Apart from two specific instances (very sh...

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  • What we may have missed
    Michael A. Colvin

    Two alternative explanations are given by Professor Taylor for the global problem with ADHD diagnosis, but he overlooks one interesting possibility- perhaps the reported prevalences are about right. That is, perhaps the rates really do vary considerably between populations and are rising in the USA and in other countries.

    Professor Taylor recognises some obvious facts. Firstly, there is a large unmet need. Seco...

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  • Re: What we may have missed
    Eric Taylor

    Thanks to Dr Colvin for his interest. I should like to clarify that an "unspoken assumption" of genetic determinism did not underlie my review. I agree with his points on the aetiology: the balance of genetic and environmental influences and their interaction deserve much more study. The aetiology, however, is an issue rather separate from prevalence. Even if countries did differ in their actual rates (rather than just...

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  • The Prevalence of ADHD is 5% in Childhood.
    Michael A. Colvin

    Professor Taylor, quoting a sound meta-analysis by Polanczyk et al published 16 years previously, declares that the prevalence of ADHD is around 5%. He appears convinced that the prevalence has not changed and does not change, and he explains that rates which differ from around 5% are either due to over-diagnosis or under-diagnosis.

    I hope I am not being impudent in suggesting that the professor has a rather in...

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  • letter in response to How do we ensure safe prescribing for children
    SW Nicholls

    Sir

    Your recent Perspective, ‘How do we ensure safe prescribing for children’ (1) highlighted an important and potentially avoidable cause of morbidity and mortality in childhood. We would like to add that significant errors in paediatric prescribing happen at the dispensing stage too, with between 2 and 58% of drug errors being related to dispensing errors (2). We briefly describe a case which highlights this...

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  • The challenges of communication to address Moral Distress
    Trisha Prentice

    We thank Dr Kraemer for his constructive response and commend his initiative to facilitate weekly staff meetings within neonatal intensive care units. We concur that communication is an essential component of addressing not only moral distress but improving workplace culture.

    As Dr Kraemer notes, finding the best forum for such discussions continues to be challenging. In our various institutions we continue to...

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  • The lost children
    brian mcnicholl

    Wright and Wales highlight the issues of childhood obesity but there is a lack of clear guidance on who should deal with it. The suggestion to " opportunistically discuss a childs weight" is easier said than done. Whose responsibility is it ? There is little immediate consequence if it is not done. Obesity is rarely the presenting complaint to a doctor. So tackling obesity, in addition to the primary complaint is two co...

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  • Integrated services for infants, children and young people
    Elaine P Lockhart

    This article helps us think about how we would like to provide services to infants, children and young people (ICYP) in response to changing needs, financial constraints and a push for multi-agency integrated working. We propose that paediatric services should have integrated mental health expertise in primary care, community and hospital based services. This would allow for prevention and early intervention, development...

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  • Conclusions not justified by findings
    Charlotte M Wright
    It is encouraging to see a clinical service making an effort to examine the patterns of growth found in their condition. However the conclusions drawn from their data seem greatly overstated. They describe a pattern of 'progressive growth failure' in nearly a quarter of children with ataxia telangiectasia (AT), yet there is an average decline across all children of less than half a centile space over 3 years. These children are...
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