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Cutaneous Langerhans cell histiocytosis presenting in a neonate
  1. Katherine J Pettinger1,
  2. Lea Solman2,
  3. Bipin Mathew3,
  4. Gayle Taylor2,
  5. Sheila Clark2,
  6. Susan Picton4
  1. 1Neonatal Unit, Leeds General Infirmary, Leeds, UK
  2. 2Department of Dermatology, Chapel Allerton Hospital, Leeds, UK
  3. 3Department of Cellular Pathology, St James’s Hospital, Leeds, UK
  4. 4Department of Paediatric Oncology and Haematology, Leeds General Infirmary, Leeds, UK
  1. Correspondence to Dr Katherine J Pettinger, Neonatal Unit, Leeds General Infirmary, Great George Street, Leeds, LS1 3EX, UK; katherine.pettinger{at}nhs.net

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A newborn boy presented at birth with a firm erythematous nodule, measuring 25×18 mm on the medial aspect of his left shin below the knee (figure 1). The lesion had a depressed centre covered with a crust and subtle telangiectasia on the edges. The rest of the examination was normal. He had been born at term following an uncomplicated pregnancy.

Figure 1

Erythematous nodule measuring 25×18 mm on the medial aspect left shin.

A 4 mm punch biopsy of the lesion was performed, revealing S100 …

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