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National Institute of Health and Care Excellence (NICE) guidelines recommend that amoxicillin is prescribed for suspected sepsis in infants under 3 months old in order to provide cover for Listeria monocytogenes infection.1 Following the article of Okike et al2, we present further evidence supporting the suggestion that prescription of routine amoxicillin should be limited solely to infants aged under 30 days.
Infection with Listeria monocytogenes is rare, particularly outside the neonatal period. Over the past decade, only 120 cases of Listeria have been isolated in infants throughout England and Wales, with 97.5% (N=117) occurring in the first month of life.3 The three remaining babies were aged 3, 6 and 11 months. …