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Authors' response to ‘Aspirin dose for treatment of Kawasaki disease’
  1. Despina Eleftheriou1,
  2. Michael Levin2,
  3. Delane Shingadia3,
  4. Robert Tulloh4,
  5. Nigel Klein1,
  6. Paul Brogan1
  1. 1Institute of Child Health and Great Ormond Street, London
  2. 2Paediatric Infectious Diseases Group, Division of Medicine, Imperial College London
  3. 3Great Ormond Street Hospital, London
  4. 4Department of Paediatric Cardiology, Bristol Royal Hospital for Children, Bristol, UK
  1. Correspondence to Dr Despina Eleftheriou, Institute of Child Health, 30 Guilford Street, London WC1E1NH, UK; d.eleftheriou{at}

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We read with interest the letter by Dr Krasseman1 regarding anti-inflammatory doses of aspirin used in the acute phase of Kawasaki disease (KD). Indeed, higher doses of aspirin are currently used in the USA (80–100 mg/kg/day), while in Japan a lower dose of 30–50 mg/kg/day is advocated.2–6 Similarly, in the UK, the latter modest dose has been recommended since 20027 ,8 for the acute phase of KD as a number of previous studies have suggested this lower dose is equally as effective, and may be associated with less toxicity.2 ,4 …

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