Skin signs as early manifestations of Hutchinson-Gilford progeria syndrome
- Angelo Massimiliano d’Erme1,
- Maria Francesca Gola2,
- Mauro Paradisi3,
- Francesca Passarelli3,
- Nicola Milanesi1,
- Massimo Gola1
- 1Division of Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
- 2Traditional Chinese Medical Center, “Fior di Prugna”, Florence Health Authority, Florence, Italy
- 3IDI-IRCCS, Rome, Italy
- Correspondence to Dr Angelo Massimiliano D’Erme, Division of Dermatology, Department of Critical Care Medicine and Surgery, Piazza Indipendenza, 11 50129 Firenze, Italy; a.m.derme{at}gmail.com
- Accepted 15 April 2012
- Published Online First 9 June 2012
Hutchinson–Gilford progeria syndrome (HGPS) is a rare, sporadic, autosomal dominant genetic disorder with phenotypic features of accelerated ageing due to a mutation of the lamin A (LMNA) gene. It arises in infancy and generally leads to death at approximately the age of 13 years.1,–,5 We report the case of a 7-month-old baby with HGPS …
