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Arch Dis Child doi:10.1136/archdischild-2011-301496
  • Letters

Postexposure chickenpox prophylaxis in children with leukaemia: a reply to the recent PEPtalk study and report of a service evaluation in a tertiary paediatric haematology centre in the UK

  1. Ajay J Vora3
  1. 1Department of Haematology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK
  2. 2Department of Microbiology, Northern General Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK
  3. 3Department of Paediatric Haematology, Sheffield Children's Hospital NHS Trust, Sheffield, UK
  1. Correspondence to Clare V Samuelson, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Department of Haematology, Glossop Road, Sheffield S10 2JF, UK; csamuelson{at}nhs.net
  1. Contributors There are no other contributors involved. CVS is the lead author who reviewed the relevant literature, collaborated in study design and data collection, and wrote the report. RR helped with study design and data collection, and commented on the final report. AJV initiated the study and oversaw its completion, giving advice on study design and write-up.

  • Received 30 December 2011
  • Accepted 7 February 2012
  • Published Online First 20 April 2012

A recent paper by Bate et al (‘PEPtalk: postexposure prophylaxis against varicella in children with cancer’)1 reports national data regarding practice in postexposure prophylaxis (PEP) of chickenpox in immunocompromised children. We provide additional depth of detail regarding practice in a large tertiary paediatric haematology unit in England by presenting a service evaluation of postexposure chickenpox prophylaxis in children with leukaemia. We also highlight the probability of underestimated cases of PEP and clinical chickenpox in the paper by Bate et al.

While chickenpox in healthy children is normally mild and self-limiting, in immunocompromised …

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