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Postexposure chickenpox prophylaxis in children with leukaemia: a reply to the recent PEPtalk study and report of a service evaluation in a tertiary paediatric haematology centre in the UK
  1. Clare V Samuelson1,
  2. Reena Rambani2,
  3. Ajay J Vora3
  1. 1Department of Haematology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK
  2. 2Department of Microbiology, Northern General Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK
  3. 3Department of Paediatric Haematology, Sheffield Children's Hospital NHS Trust, Sheffield, UK
  1. Correspondence to Clare V Samuelson, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Department of Haematology, Glossop Road, Sheffield S10 2JF, UK; csamuelson{at}nhs.net

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A recent paper by Bate et al (‘PEPtalk: postexposure prophylaxis against varicella in children with cancer’)1 reports national data regarding practice in postexposure prophylaxis (PEP) of chickenpox in immunocompromised children. We provide additional depth of detail regarding practice in a large tertiary paediatric haematology unit in England by presenting a service evaluation of postexposure chickenpox prophylaxis in children with leukaemia. We also highlight the probability of underestimated cases of PEP and clinical chickenpox in the paper by Bate et al.

While chickenpox in healthy children is normally mild and self-limiting, in immunocompromised …

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