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Cardiovascular dysfunction in infants with neonatal encephalopathy
  1. Katey Armstrong1,2,3,
  2. Orla Franklin2,
  3. Deirdre Sweetman1,3,
  4. Eleanor J Molloy1,3,4,5
  1. 1Department of Paediatrics, National Maternity Hospital, Dublin, Ireland
  2. 2Department of Paediatric Cardiology, Our Lady's Children's Hospital, Dublin, Ireland
  3. 3National Children's Research Centre, Dublin, Ireland
  4. 4Royal College of Surgeons in Ireland, Dublin, Ireland
  5. 5UCD School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland
  1. Correspondence to Katey Armstrong, Department of Paediatrics, National Maternity Hospital, Holles St, Dublin 2, Ireland; katey21{at}hotmail.com

Abstract

Severe perinatal asphyxia with hypoxic ischaemic encephalopathy occurs in approximately 1–2/1000 live births and is an important cause of cerebral palsy and associated neurological disabilities in children. Multiorgan dysfunction commonly occurs as part of the asphyxial episode, with cardiovascular dysfunction occurring in up to a third of infants. This narrative paper attempts to review the literature on the importance of early recognition of cardiac dysfunction using echocardiography and biomarkers such as troponin and brain type natriuretic peptide. These tools may allow accurate assessment of cardiac dysfunction and guide therapy to improve outcome.

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Footnotes

  • Funding National Children's Research Centre, Crumlin, Dublin, Ireland.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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