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NICE recommendations for the formal assessment of babies with prolonged jaundice: too much for well infants?
  1. M E Rodie1,
  2. A Barclay2,
  3. C Harry3,
  4. J Simpson4
  1. 1Department of Child Health, Royal Hospital for Sick Children, Glasgow, UK
  2. 2Department of Gastroenterology, Royal Hospital for Sick Children, Glasgow, UK
  3. 3Community Paediatrics, Rainbow House, Ayrshire Central Hospital, Irvine, North Ayrshire, UK
  4. 4Neonatal Intensive Care Unit, Royal Hospital for Sick Children, Glasgow, UK
  1. Correspondence to Dr Martina Rodie, Department of Child Health, Royal Hospital for Sick Children, Dalnair St, Yorkhill, Glasgow G3 8SJ, UK; martinarodie{at}hotmail.com

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Prolonged jaundice (PJ) is common, affecting 2–15% of all neonates and up to 40% of breastfed infants.1 It presents a challenge to health professionals, who must identify those infants with pathology while avoiding the unnecessary investigation of normal babies. National Institute for Health and Clinical Excellence (NICE) recently recommended, that in addition to a thorough examination, the formal assessment of PJ should include conjugated bilirubin, urine culture, glucose-6-phosphate dehydrogenase where ethnically appropriate, full blood count, blood group determination and Coomb's test.2

The three studies referenced had methodological flaws, including all …

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