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Subclinical hypothyroidism in childhood
  1. MJ O'Grady,
  2. D Cody
  1. Department of Endocrinology and Diabetes, Our Ladys Childrens Hospital, Crumlin, Dublin, Ireland
  1. Correspondence to Dr D Cody, Department of Endocrinology and Diabetes, Our Ladys Childrens Hospital, Crumlin, Dublin 12, Ireland; Declan.cody{at}olchc.ie

Abstract

Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) in association with a normal total or free thyroxine (T4) or triiodothyronine (T3). It is frequently encountered in both neonatology and general paediatric practice; however, its clinical significance is widely debated. Currently there is no broad consensus on the investigation and treatment of these patients; specifically who to treat and what cut-off level of TSH should be used. This paper reviews the available evidence regarding investigation, treatments and outcomes reported for childhood SH.

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Footnotes

  • Provenance and peer review Commissioned; externally peer reviewed.

  • Patient consent Not obtained.

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