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Cerebrovascular disease and stroke
  1. John Pappachan (john.pappachan{at}
  1. Southampton University hospitals NHS Trust, United Kingdom
    1. Fenella Kirkham (f.kirkham{at}
    1. UCL Institute of Child Health, United Kingdom


      Stroke and cerebrovascular disorders are important causes of morbidity and mortality in children, already amongst the top 10 causes of childhood death and probably increasing in prevalence. Acute treatment of stroke syndromes in adults is now evidence-based. Paediatric stroke syndromes are very much less common and the differential diagnosis is very wide but the individual health resource implications are much greater because of the life long treatment costs in survivors. Recognition and consultation with a paediatric neurologist should be rapid so that children can benefit from regional services with emergency neurological, neuroradiological and neurosurgical intervention and paediatric intensive care.

      This review focuses on the epidemiology, presentation, differential diagnosis, generic/specific emergency management and prognosis of acute stroke in children. Its aim is to educate and guide management by general paediatricians and to emphasise the importance of local guidelines for the initial investigation and treatment and appropriate transfer of these children.

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