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Is this immune thrombocytopenic purpura?
  1. Jecko Thachil (jeckothachil{at}
  1. Royal Liverpool University Hospital, United Kingdom
    1. Georgina W Hall (georgina.hall{at}
    1. Children's Hospital, John Radcliffe Hospital, United Kingdom


      When a well child comes to Accident and Emergency (A & E) with a history of sudden onset bruising, purpura and petechiae, and is found to have an isolated severe thrombocytopenia, the diagnosis is usually obvious: acute Immune Thrombocytopenic Purpura (ITP). But, could something more sinister be going on? Is ITP the correct diagnosis?

      This article outlines the features that should worry a clinician, making them suspicious of an alternative diagnosis. Aware of the possible differential diagnoses the clinician can appropriately investigate and manage the child with ITP, and know when to refer to a paediatric haematologist for specialist help.

      • immune thrombocytopenic purpura
      • thrombocytopenia

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