Objective To analyse the sensitisation status to common inhalant allergens of suspected allergic children in Beijing Childrens’ Hospital in the year of 2013.
Methods Between January 2013 and January 2014, there are a total of 21134 cases conducted the allergen screening testing (Medswiss AllergyScreen allergen testing system, Germany). According to the department at first visit of outpatient children and the major clinical diagnostic information of the inpatient children, the out-patient children or the in-patient children could be further divied into subgroups accordingly. A comparison in the differences of allergen sensitisation pattern between ward patients and outpatients was performed.
Results In the out-patient subjects, the positive rate of sIgE was 45.99% (8266/17974 cases),the top three positive rate of inhalant allergen were mould (18.57%), dog hair (16.54%) and dust mites (15.69%). However, in the outpatients, the positive rate of sIgE was 29.34% (927/3160 cases)and the top three positive detection rate were dust mites (10.95%), dog hair (8.48%), and the mould (7.95%) in turn. It was also found that the positive ratio of children suffering from the nose or eye disease (from ear-nose-throat, head and neck surgery and ophthalmology out-patient: 2092/3126 cases, 66.92%; from ear-nose-throat of head and neck surgery and ophthalmology ward: 14/26 cases, 53.85%) were significantly higher than the others. Besides, it was considered that the Henoch-Schonlein purpura (HSP)is one kind of disease that closely related with the sensitisation condition.
In this study, the positive rate to inhaled allergens in HSP childrens was significantly higher than that in non-HSP childrens (HSP: 520/1375 cases, 37.80%; non-HSP: 407/1782 cases, 22.80%, p < 0.0001).
Conclusion The allergen screening testing is not only useful in the rapid assessment of body sensitisation state, but also play a positive role in the providing rational allergen avoidance advise. Therefore, it should be to pay more attention in the combination and translation between the allergen screening results and the clinical information.