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PO-0335 Does The Nebulized 3% Hypertonic Saline Solution Reduce Admissions To Picu In Acute Bronchiolitis?
  1. JC Flores-Gonzalez1,
  2. P Comino-Vazquez1,
  3. P Rodriguez-Campoy1,
  4. G Jimenez-Gómez2,
  5. MA Matamala-Morillo1,
  6. RM Garcia-Ortega1,
  7. JJ Perez-Guerrero1,
  8. L Garcia-Garcia1,
  9. FJ Dávila-Corrales1,
  10. B Serrano-Moyano1,
  11. E Palma-Zambrana1,
  12. AM Lechuga-Sancho3
  1. 1Pediatrics Department, Hospital Universitario Puerta Del Mar, Cádiz, Spain
  2. 2Research Unit, Hospital Universitario Puerta Del Mar, Cádiz, Spain
  3. 3Cadiz University, Hospital Universitario Puerta Del Mar, Cádiz, Spain

Abstract

Background and aims Nebulised 3% hypertonic saline (3%HSS) decreases length of hospitalisation and rate of admission in infants with moderate bronchiolitis. To describe whether treatment with nebulised 3%HSS, with or without bronchodilators in acute moderate bronchiolitis, decreases the rate of admission to PICU compared to nebulised saline (FSS) with bronchodilators.

Material and methods 389 patients with moderate acute bronchiolitis were admitted, 181 were collected retrospectively (group 0: October 2008 to May 2010) and 208 prospectively (group 1: October 2011 to May 2013 patients). Group 0 received treatment with FSS and group 1 received 3%HSS. The PICU admission rate was recorded as the main variable. Secondary variables: overall hospital length of stay (LOS), stay at PICU, need for mechanical ventilation (MV) and its duration. The collected variables were analysed using Chi – square and nonparametric tests.

Results Demographic data and clinical data were similar in both groups (p > 0.05): mean age, gender male, RSV positive, corticosteroids or antibiotics use. LOS was longer in group 0 (p = 0.020). PICU admission was 17.8% vs 12.5%, p = 0.146, stay PICU: 5.91 days vs 3.76 days, p = 0.859), VM rate in PICU was 25% vs 24%, p = 0.931 and VM duration of PICU was 7.63 days vs 7.17 days.

Conclusions Patients treated with 3%SSH showed the same PICU admission rate and stay. The nebulised 3%SSH does not decrease the PICU admission. Overall hospital LOS was longer in FSS group.

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