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PO-0279 Skin Conductance Changes Differ Between Painful Stimuli And General Hypoxia Different From Peripheral Oxygen Saturation
  1. B Nakstad1,
  2. T Nordheim1,
  3. H Hovde2,
  4. AL Solevåg2,
  5. M Thorud2,
  6. H Storm3
  1. 1Pediatric and Adolescent Medicine, University of Oslo and Akershus University Hospital, Lorenskog, Norway
  2. 2Pediatric and Adolescent Medicine, Akershus University Hospital, Lorenskog, Norway
  3. 3University of Oslo, Institute of Clinical Medicine, Oslo, Norway

Abstract

Background and aims Peripheral oxygen saturation (SpO2) decreases during general hypoxia and painful events in preterm infants. Skin conductance responses per sec (SCR/sec) increase during painful procedures. The purpose of this observational study was to examine if SCR/sec can help to diagnose if SpO2 is due to general hypoxia or painful events.

Methods Ten infants, diagnosed as ventilator unstable with birth weight 1248 (± 710) grams, gestational age 30 (± 5) weeks and at postnatal day 3 (± 1) were observed for 1 h when venous blood sampling was performed. SpO2, SCR/sec, heart rate (HR), and respiratory rate (RR) were recorded each 2nd minute and during the painful and hypoxic events (defined as SpO2 lower than 80%). The variables were studied during the painful and hypoxic events as well as in situations without events. Non-parametric tests for within individual variables (Friedman’s Anova) were used.

Results There were statistical differences for physiological measures during the no- painful- and hypoxic events; mean (SD):

Abstract PO-0279 Table 1

Conclusion SCR/sec does not increase during SpO2 and may be used to differ between pain and general hypoxia in preterm infants.

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