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PO-0108 Rotavirus Gastroenteritis Among Children Less Than 5 Years: A Cross Sectional Study On Demographic, Clinical, Laboratory And Treatment Profile
  1. J Cheriathu1,
  2. L Jenny John2,
  3. E Ignatius Dsouza1,
  4. M Shamseldeen1
  1. 1Pediatrics, Gulf Medical University, Ajman, United Arab Emirates
  2. 2Pharmacology, Gulf Medical University, Ajman, United Arab Emirates

Abstract

Introduction Rotavirus is leading cause of severe diarrhoea (about 20%) among infants and children and necessitating hospitalisation. The frequency of rotavirus infection among the admitted children <5 years with gastroenteritis and their demographic, clinical, laboratory and treatment profile was studied.

Material and methods Hospital based study carried out among <5 years children with acute gasteroenteritis (AGE) admitted to Paediatric ward, from January 2011–December 2012.

Demographic characteristics, clinical history, laboratory investigations studied.

SPSS version 20 software used for Statistical analysis. Chi-square test and t- test were used to compare variables.

Results 970 cases of AGE of age <5 years admitted during study period.

240 cases (24.7%) - Rotavirus gasteroenteritis (RVGE), 46 cases- Amebiasis, 8 Adenovirus infection.

57% of RVGE males.

Nationality: Majority from Middle-East; (22% Egypt) (18% UAE Nationals)

62% RVGE <2 years.

Diarrhoea, Vomiting and fever were the frequent presenting symptoms in all cases.

79% of the cases presented with Moderate degree of dehydration.

Mean total leucocyte count (TLC) was 9738.4 (3888.2) among RVGE; 11454.2 (4407.3) in amebiasis group (p < 0.05).

Mean CRP value- 9.8 (16.6) mg/L in RVGE; 50.3 (82.3) mg/L in amebiasis group (p < 0.001).

Stool examination showed significant difference in colour, consistency, presence of mucus and blood between RVGE and Amebiasis group.

Mean duration of hospital stay was 2(1) days in both RVGE and other AGE group.

No mortalities noted.

Conclusion Frequency, age distribution, clinical characteristics of RVGE are similar to other reports from Middle East.

Stool characteristics, Laboratory parameters help to differentiate AGEs, IL6, faecal lactoferrin more specific for differentiating various AGEs.

Routine Rotavirus Immunisation recommended.

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