Article Text

PO-0016 Henoch Scholein Purpura In Children: About 24 Cases
  1. I Maaloul,
  2. L Sfaihi,
  3. J Telmoudi,
  4. Y Bel Fitouri,
  5. H Aloulou,
  6. TH Kamoun,
  7. M Hachicha
  1. Pediatric Department, CHU Hedi Chaker Sfax Tunisia, Sfax, Tunisia

Abstract

Background Henoch Scholein Purpura is the most frequent vasculitis in children. Its diagnosis is clinical and prognosis is often favourable.

Aim To precise the epidemiological, clinical, biological profiles and course of the disease.

Methods Retrospective study over 10 years (January 2005–January 2014) of 24 children with Henoch-schonlein vasculitis. The diagnosis was based on the association of non-trombocytopenic purpura, arthritis or arthralgia and abdominal pain.

Results The mean age of patients was 5,2 years with male predominance (sex-ratio: 1.8). Purpura was observed in all cases. Articular manifestations were noted in 16 cases (69, 5%). Digestive manifestations were noted in 11 cases; it involves acute gastro-intestinal bleeding (4 cases), abdominal pain (6 cases) and diarrhoea (1 case). Upper digestive gastrointestinal endoscopy was done in 3 cases; it showed erosive gastritis in one case. Ultrasonography showed intussusception in 2 patients. Moderate renal manifestations (microscopic hematuria, moderate proteinuria) were observed in 5 children. Five patients required corticosteroid therapy. The evolution was favourable in all cases.

Conclusion The Henoch-Sconlein purpura is generally a benign disease. prognosis depends on the risk digestive complications at the acute phase and renal damage at long-term.

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