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PS-170a Lenticulostriate Vasculopathy In Preterm Infants At Term Corrected Age
  1. P Nongena1,
  2. A Ederies1,
  3. V Wardley1,
  4. N Hayward1,
  5. J Wurie2,
  6. N Gonzalez-Cinca1,
  7. D Azzopardi2,
  8. S Counsell2,
  9. M Rutherford2,
  10. N Kennea3,
  11. Edwards A.D.2 on behalf of the ePrime study
  1. 1Paediatrics, Imperial College London, London, UK
  2. 2Centre for the Developing Brain, Kings College London, London, UK
  3. 3Neonatology, St George’s Healthcare NHS Trust, London, UK


Introduction The aim of this study was to define the incidence Lenticulostriate Vasculopathy detected by cranial ultrasound (US) in a large group of preterm infants recruited to the Evaluation of Preterm Imaging Programme (ePrime).

Methods We studied 511 of 2133 eligible infants admitted to 13 neonatal units including 5 Perinatal Centres. 254 were male and 84 from multiple pregnancies. Median (range) gestational age (GA) was 30 (23–32) weeks and birthweight 1270 (552–3160) g. Cranial ultrasound images were obtained at 38–44 weeks GA in 479 and 44–60 weeks GA in 32 infants, and reported using conventional diagnostic criteria.

Results Cranial ultrasound scans were available for 509 infants. Lenticulostriate Vasculopathy was detected in 143 infants (28%). Preliminary analysis found no relation was detected to multiple pregnancy, birthweight, surfactant or antenatal steroid therapy, length of respiratory support, treatment for patent ductus arteriosus or other cranial ultrasound abnormality.

Conclusions Lenticulostriate Vasculopathy was common in this group of infants. Further work is warranted to determine the aetiology and prognostic value of this common MR finding.

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