Aim To evaluate the influence of bifidobakterium lactis 2011 and hindiba inulin on feeding intolerance and necrotising enterocolitis in premature babies
Material and method 89 premature babies with the diagnosis of feeding intolerance were enrolled in the study. Premature babies were divided into two groups; Study group (group 1) had Bifidobakterium Lactis (5 × 109 CFU) + Hindiba Inulin (900 mg) (MaflorR) liquefied with 10 ml sterile water with the dosage of 3 × 1 ml peroral while control group (group 2) did not have any medication for feeding intolerance.
Results Gender and gestational weeks of the groups were not significantly different. B. Lactis ve Hindiba Inulin was started at mean 9.9 days and continued for mean 11.1 days. Time of starting oral feeding and time of full enteral feeding were longer in study group and this was statistically significant. (p < 0,05). Although NEC was not significantly different between groups (p > 0,05), babies in the study group diagnosed as in Grade 1 and did not progress, one third of the diagnosed babies in the control group progressed to Grade 2. When the groups were compared according to weight gain, study group gained more weights and it was statistically significant. (p < 0,05).
Conclusion Probiotics and prebiotics may have positive effect due to higher weight gain and not advancing in NEC in study group having B. Lactis and Hindiba Inulin.