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Towards evidence based medicine for paediatricians
  1. Bob Phillips
  1. Correspondence to Dr Bob Phillips, Centre for Reviews and Dissemination, University of York, York YO10 5DD, UK; bob.phillips{at}doctors.org.uk

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Compared with standard care

There’s a decent argument in the analysis of quantitative studies of therapies, particularly using randomised controlled trial designs, that says that we should be looking at the totality of unbiased evidence (systematic reviews) rather than looking at individual, cherry-picked, studies. The best estimate from this comes from a pooling of all the results: meta-analysis.

There’s a challenge to this, though, when the comparisons are not quite the same. In the …

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