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Hypotonic fluids and hyponatraemia

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Readers in Northern Ireland will be well aware of a long-running government inquiry into the deaths of a number of children in the province, over a decade ago, attributed to iatrogenic hyponatraemia. Partly as consequence of these events, a UK National Patient Safety Authority alert was issued in 2007, warning us of the dangers of routine use of hypotonic intravenous fluids. Since then, there have been several systematic reviews of the literature. The latest (Wang …

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