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Tuberculous paradoxical reaction with bone involvement
  1. Daniel Blázquez,
  2. David Aínsa-Laguna,
  3. Jesús Ruíz-Contreras
  1. Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitario 12 de Octubre, Madrid, Spain
  1. Correspondence to Dr Daniel Blázquez, Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitario 12 de Octubre, Avda de Córdoba sn,Madrid 28041, Spain; danielblazquez{at}hotmail.com

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Between 10% and 14% of children treated for tuberculosis (TB) have a paradoxical reaction (a worsening of pre-existing TB lesions or development of new lesions after initial improvement).1 ,2 Only one case of paradoxical reaction in bone has been previously reported in a child.2

A 17-month-old boy presented with cough, lower lobe infiltrate in the right lung with mediastinal lymphadenopathy, …

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