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328 Validation of Eric - A New Parental Report Instrument for Detection of Cognitive Delay in At-Risk Infants
  1. G Schafer1,
  2. L Genesoni1,
  3. R Jones2,
  4. HA Doll3,
  5. E Adams4,
  6. R Gray5,
  7. G Boden6
  1. 1Department of Psychology, University of Reading, Reading
  2. 2Paediatric Department, Wexham Park Hospitals, Slough
  3. 3Department of Population Health, Norwich Medical School, Norwich
  4. 4Neonatal Unit, John Radcliffe Hospital
  5. 5National Perinatal Epidemiology Unit (NPEU), University of Oxford, Oxford
  6. 6Neonatology, Royal Berkshire Hospital, Reading, UK

Abstract

Background and Aims At 2 years, cognitive delay is the most common form of developmental disability in the preterm population (Marlow, 2004). We have established the diagnostic properties of a new cognitive developmental screen (Early Report by Infant Caregivers, ERIC), between 10–24 months.

Methods Participants. 362 infants aged 10–24 months, with at least one of: weight < 1500g, < 34 completed weeks gestational age, 5-min Apgar < 7, HIE. Children with impairments preventing fair assessment by ERIC were excluded. Parents/caregivers completed ERIC at home before administration of the Cognitive Scale of the Bayley Scales of Infant Development III. Delay was defined as a prematurity-corrected Bayley score < 80 (Moore et al, 2011).

Results Nineteen infants were delayed, with age-corrected ERIC scores lower than those without delay (p<0.001). On ROC analysis, Area Under the Curve was 0.86, with 83% sensitivity (95% CI 66–99.9%), 79% specificity (75–83%), 19% Positive Predictive Value (PPV) (2–36%), and 98% Negative Predictive Value (NPV) (96–99.6%). The low PPV reflects low prevalence of delay (5.2%) in this sample.

Conclusions ERIC provides a useful diagnostic screening tool, able to rule out developmental delay in this population (NPV = 98%).

Note This abstract presents independent research funded by the National Institute for Health Research (NIHR) under its Research for Patient Benefit (RfPB) Programme (Grant Reference PB-PG-0807–14202). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. Preliminary results were presented to the Neonatal Society, London, March 2012.

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